Tachycardia, palpitation, ECG changes, arrhythmias, hypotension, and hypertension have been reported. 10, FD&C Blue No. privacy practices. Does Vicks DayQuil oral interact with other drugs you are taking? (2000): 205-13, Haller CA, Benowitz NL "Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids." American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Accessed April 6, 2022. (1987): 399-404, Kikta DG, Devereaux MW, Chandar K "Intracranial hemorrhages due to phenylpropanolamine." (1993): 825-7. If you notice other effects not listed above, contact your doctor or pharmacist. Severe liver injury, including cases of acute liver failure resulting in liver transplant and death, has been reported in patients using acetaminophen. Pharmacotherapy for insomnia in adults. (2010): "Product Information. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. (1982): 359-65, Simons KJ, Simons FE, Luciuk GH, Frith EM "Urinary excretion of chlorpheniramine and its metabolites in children." 4 In studies of older adults, diphenhydramine reduced awakenings but didn't improve sleep latency, total sleep time, or sleep quality. Major Potential Hazard, Moderate plausibility. Tylenol, aspirin, or ibuprofen mixed with codeine and cyclobenzaprine can boost euphoric effects if the person hasnt eaten. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. (1986): 2636-7, Seeff LB, Cuccherini BA, Zimmerman HJ, Adler E, Benjamin SB "Acetaminophen hepatotoxicity in alcoholics." Overdose symptoms may include extreme drowsiness, irritability, dilated pupils, hallucinations, or seizure. In doing so, diphenhydramine can cause sleepiness. Moderate Potential Hazard, Moderate plausibility. (1988): 339-43, Bernstein E, Diskant BM "Phenylpropanolamine: a potentially hazardous drug." If you, or a loved one, are abusing opiates, with or without potentiators, immediate intervention and treatment are essential. Abbott Pharmaceutical The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. JAMA 272 Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. In patients with other forms of glaucoma, mydriasis may occasionally increase intraocular pressure. The study uses data from the FDA. It is often used in motion sickness. Accessed April 6, 2022. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Understanding Withdrawal & Detox by Substance. Am J Hypertens 14(9 Pt 1) Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Merck & Co., Inc Available for Android and iOS devices. Combining opiate drugs with any other medications or substances comes with many risks, as potential interactions may occur. Dramamine offers dosing instructions for children as young as 2 years old. Instruct patients to avoid drinking alcohol while taking acetaminophen-containing medications. Follow all directions on your medicine label and package. Moderate Potential Hazard, High plausibility. All rights reserved. Wyeth-Ayerst Laboratories (1999): Maddox DE, Reed CE "Clinical pharmacodynamics of antihistamines." Store at room temperature away from moisture and heat. We compare the side effects and drug effectiveness of Nyquil and Dramamine. Mayo Clinic does not endorse companies or products. Ann Emerg Med 11 loss of . 2005 - 2023 WebMD LLC. Otherwise, call a poison control center right away. 2005 - 2023 WebMD LLC. Email this report to a friend, doctor, or patient, Vicks NyQuil Severe Cold & Flu consumer information, Drug class: upper respiratory combinations. Ferri FF. Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. We study millions of patients and 5,000 more each day. Temaril (trimeprazine)." Chronic alcohol abusers may be at increased risk of hepatotoxicity during treatment with acetaminophen (APAP). This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Dramamine Nyquil Dramamine and Nyquil drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported only by a few people who take Dramamine and Nyquil together. (1983): 71-3, Elliott CF, Whyte JC "Phenylpropanolamine and hypertension." Adding oatmeal, cornstarch, or baking soda to liquid opiates creates a solid that can be ingested as well. Does Dramamine Less Drowsy interact with other medications? Are you covered for addiction treatment? Intermezzo (zolpidem)." Find your insurance. Drinking alcohol with this medicine can cause side effects. Equanil (meprobamate)." Optimine (azatadine)." Sanja Jelic, MD, is board-certified in sleep medicine, critical care medicine, pulmonary disease, and internal medicine. Some reports may have incomplete information. Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, overactive thyroid (hyperthyroidism), trouble urinating (such as due to enlarged prostate), use/abuse of alcohol. Neurology 43 Diphenhydramineis a common ingredient in sleeping aids; it is also used to treat allergies. Moderate Potential Hazard, High plausibility. sanofi-aventis * Approximation only. Moderately clinically significant. Abraham O, et al. Different individuals may respond to medication in different ways. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Otolaryngol Head Neck Surg 111 Suppl Am J Med 85 Patients with hepatic impairment may be at increased risk of toxicity due to increased minor metabolic pathway activity. Ask your doctor when to start or stop taking this medication. You're basically making NyQuil, which has diphenhydramine as the antihistamine. Applicable conditions: Phenylketonuria. Both Xanax (alprazolam) and NyQuil (acetaminophen, dextromethorphan, and doxylamine) can potentially cause respiratory depression, sedation, and other CNS effects. Antihistamine Aficionado Magazine has indicated many other ways opioids could be potentiated with other substances. "Product Information. (1985): 405-7, Caperton E "Raynaud's phenomenon. Therapy with sympathomimetic agents should be administered cautiously in patients with or predisposed to glaucoma, particularly narrow-angle glaucoma. (2002): "Product Information. Before having surgery, tell your doctor or dentist that you are taking this medication. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Most sleep aids available without a prescription contain antihistamines. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Poly-Histine-D (pyrilamine)." Diphenhydramine is an antihistamine. J Allergy Clin Immunol 70 Accessed April 6, 2022. The use of potentiators is exacerbating the issue of opiate abuse. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Neurology 37 Mayo Clinic Minute: Sleep Spoiler - Tips for a Good Night's Rest. Antihistamines may infrequently cause cardiovascular adverse effects related to their anticholinergic and local anesthetic (quinidine-like) activities. "Product Information. Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Vyvanse Interactions. Industry Accreditations, Reviews & Ratings. DayQuil doesn't have an antihistamine in it (which is why it doesn't make you drowsy), and Dramamine (dimenhydrinate) is an antihistamine, you can take them together. There may also be drying effects. These may manifest as: Urinary retention may increase the risk of developing urinary tract infections (UTIs) or affect kidney function. Lower initial dosages may be appropriate. Even with seemingly harmless everyday substances, unintended consequences may arise at any time, and combining substances increases the potential for overdose. Yeah, I will! JAMA 255 (1985): 510-2, Clark JE, Simon WA "Cardiac arrhythmias after phenylpropanolamine ingestion." Highly clinically significant. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Several oral acetaminophen and acetaminophen-combination products, particularly flavored chewable tablets, contain the artificial sweetener, aspartame (NutraSweet). (1985): 688-91, Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 Do not use extra medicine to make up the missed dose. Ann Intern Med 104 Sudafed (pseudoephedrine)." Stuff like Dramamine or NyQuil don't really make me sleepy when I'm sick. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. To provide you with the most relevant and helpful information, and understand which Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sleep aids Understand over the counter options. (2001): "Product Information. Dextromethorphan is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. Liquid forms of some narcotics can be enhanced by mixing with antacids or sodium bicarbonate, which lengthens the high. Orphan Medical Med J Aust 2 (2001): "Product Information. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Do not increase your dose or take this medication more often than directed without your doctor's approval. (1984): 701-7, Huang SM, Athanikar NK, Sridhar K, Huang YC, Chiou WL "Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults." (1990): 195-208, Lake CR, Zaloga G, Bray J, Rosenberg D, Chernow B "Transient hypertension after two phenylpropanolamine diet aids and the effects of caffeine: a placebo-controlled follow-up study." The older you are, the greater the risk of adverse effects. (1986): 138-9, Prescott LF, Critchley JA "Drug interactions affecting analgesic toxicity." Accessed April 6, 2022. Their plasma clearance may be decreased and their half-life prolonged in patients with impaired hepatic function. (1995): 767-73, Gillette JR "An integrated approach to the study of chemically reactive metabolites of acetaminophen." The most common side effects of diphenhydramine include: drowsiness. 2017;39(4):808-817. doi:10.1007/s11096-017-0467-x, Scammell TE, Jackson AC, Franks NP, Wisden W, Dauvilliers Y. Histamine: neural circuits and new medications. Those who take a prescription painkiller or even cardiovascular medications should also ask their physician whether they can consume grapefruit. (1983): 143-5, Horowitz JD, Lang WJ, Howes LG, Fennessy MR, Christophidis N, Rand MJ, Louis WJ "Hypertensive responses induced by phenylpropanolamine in anorectic and decongestant preparations." (1996): 233-52, Glazko AJ, Dill WA, Young RM, Smith TC, Ogilvie RI "Metabolic disposition of diphenhydramine." (1987): 163-4, Lake CR, Gallant S, Masson E, Miller P "Adverse drug effects attributed to phenylpropanolamine: a review of 142 case reports." It is not known whether Dramamine will harm an unborn baby. This content does not have an English version. It is often used in motion sickness. The average age for using such medicines for the first time was 21.2. Liquid or chewable forms of this product may contain sugar or aspartame. Our phase IV clinical studies alone cannot establish cause-effect relationship. Dramamine is used to treat or prevent nausea, vomiting, and dizziness associated with motion sickness. (1986): 529-33, Albert KS, Hallmark MR, Sakmar E, Weidler DJ, Wagner JG "Pharmacokinetics of diphenhydramine in man." (1981): 375-9, Arnman R, Olsson R "Elimination of paracetamol in chronic liver disease." Some products that may interact with this drug are: anti-seizure medications (such as phenytoin, phenobarbital), beta blockers (such as metoprolol, atenolol), guanethidine, ketoconazole, levoketoconazole, methyldopa, phenothiazines (such as chlorpromazine), rolapitant, tricyclic antidepressants (such as amitriptyline, desipramine). Doxylamine succinate, the active ingredient in NyQuil, and some sleeping pills have been combined with opiates as well. Sandoz Pharmaceuticals Corporation Tacaryl (methdilazine)." Westwood Squibb Pharmaceutical Corporation (2001): . Which is the reason that you need to take Dramamine? (2002): Whitcomb DC, Block GD "Association of acetaminopphen hepatotoxicity with fasting and ethanol use." More of the drug can actually pass from the digestive system into the bloodstream, leading to respiratory failure, bleeding, and death. eHealthMe is studying from 1,222 Dramamine users for its effectiveness, alternative drugs and more. Kryger MH, et al., eds. In patients with anatomically narrow angles or narrow-angle glaucoma, pupillary dilation can provoke an acute attack. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Endo Laboratories LLC (1989): 1043-4, Pentel PR, Mikell FL, Zavoral JH "Myocardial injury after phenylpropanolamine ingestion." (1995): 301, Zimmerman HJ, Maddrey WC "Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure." Clin Pharmacol Ther 35 NyQuil Cold and Flu. A few medicines that you can get without a prescription (called over-the-counter or OTC medicines) can potentially increase seizures in people with epilepsy. Applicable conditions: Glaucoma/Intraocular Hypertension, Urinary Retention. Many unintended overdoses have occurred due to opiates across the United States. Mayo Clin Proc 77 (1983): 54-5, Lee KY, Beilin LJ, Vandongen R "Severe hypertension after administration of phenylpropanolamine" Med J Aust 1 People who eat limes or have marmalade with oranges can be at risk as well. 8 CAPSULE, LIQUID FILLED in 1 BLISTER PACK, cough due to minor throat and bronchial irritation, more than 4 doses in 24 hours, which is the maximum daily amount for this product, with other drugs containing acetaminophen, 3 or more alcoholic drinks daily while using this product. (2001): "Product Information. All information is observation-only. This medication list is not intended to be complete and additional brand names may be found for each medication. If you have any questions about storage, ask your pharmacist. Kryger M, Roth T, Dement W. Principles and Practice of Sleep Medicine - 6th Edition. Chewable and effervescent formulations of acetaminophen products may also contain phenylalanine. 2021; doi:10.1016/j.jagp.2020.10.011. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. (1992): 287-90, Loizou LA, Hamilton JG, Tsementzis SA "Intracranial haemorrhage in association with pseudoephedrine overdose." Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. How can I sleep better? It is not known whether dimenhydrinate passes into breast milk or if it could harm a nursing baby. Allergan Inc Medisca Inc Document Id: 1843dbea-0c03-4ccc-8af3-c3658ac607eb, Set id: 9631ae65-aa73-4ca2-965c-89163d673aa9, or NyQuil products, carefully read each label to insure correct dosing, acetaminophen, dextromethorphan hydrobromide, and doxylamine succinate capsule, liquid filled. Pediatrics 103 For further questions concerning your use of Advil products, please speak with a healthcare provider. Personalize this study to your gender and age, Propofol and Hydrocortisone Valerate drug interaction, Dementia Alzheimer'S Type and drugs of ingredients of estradiol, Neuropathy Peripheral and Aortic Arch Syndrome. Sleep aids available without a prescription are widely available. These can increase respiratory depression and thicken bronchial secretions. (1990): 205-10, Pentel PR, Aaron C, Paya C "Therapeutic doses of phenylpropanolamine increase supine systolic blood pressure." (2002): "Product Information. There is a problem with N Engl J Med 343 These drugs can cause or exacerbate mental depression and cause suicidal behavior and ideation. take only as directed - see Overdose warning. More than half of all over-the-counter sleep aids contain medications that block H1 receptors, such as diphenhydramine or doxylamine (found in Nyquil and Unisom). In 2014, the Centers for Disease Control (CDC) reported 78 Americans died on a daily basis from an overdose of opioids. 2015. doi:10.4088/PCC.15r01798, By the 2019 American Geriatrics Society Beers Criteria Update Expert Panel. However, some patients may be susceptible at commonly used dosages, including the elderly, debilitated or severely ill patients, those receiving other CNS depressants, and those with limited ventilatory reserve, chronic pulmonary insufficiency or other respiratory disorders. Therapy with anxiolytic, sedative, and hypnotic agents should be administered cautiously in these patients. (2014): "Product Information. Moderate Potential Hazard, Moderate plausibility. There are 15 disease interactions with Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine). You may report side effects to FDA at 1-800-FDA-1088. Therapy with acetaminophen should be administered cautiously, if at all, in patients who consume three or more alcoholic drinks a day. Through biochemical processes, the juice can actually increase the concentration of oxycodone in the body and enhance its effects. Decongestants help to relieve stuffy nose symptoms. It may be prudent to refrain from dispensing large quantities of medication to these patients. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Dosage form: capsule, liquid filled Ingredients: Acetaminophen 325mg, Dextromethorphan Hydrobromide 15mg, Doxylamine succinate 6.25mg Labeler: Lil' Drug Store Products, Inc. NDC code: 66715-9713 WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Consult your pharmacist or local waste disposal company. 2023 Dotdash Media, Inc. All rights reserved. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Nevertheless, morning side effects such as residual sleepiness or hangovercan occur. (1982): 471-2, Dickerson J, Perrier D, Mayersohn M, Bressler R "Dose tolerance and pharmacokinetic studies of L (+) pseudoephedrine capsules in man." You may report side effects to Health Canada at 1-866-234-2345. This survey is being conducted by the WebMD marketing sciences department. The opiate elements can be extracted with cold water and ingested with a syringe or medicine dropper. Bonine doesn't offer dosing for anyone younger than 12. Management of insomnia and long-term use of sedative-hypnotic drugs in older patients. Appropriate monitoring and individualization of dosage are recommended. Neurology 35 Here's what you need to know if you're considering medication to help you sleep. We comply with the HONcode standard for trustworthy health information. J Pharm Sci 73 There is 1 alcohol/food interaction with Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine). This article explores how diphenhydramine works, potential side effects, and why it's generally recommended that older adults avoid using diphenhydramine except to manage allergic reactions. Lancet 1 JAMA 244 Evidenced-based review and evaluation of clinical significance: Nonpharmacological and pharmacological treatment of insomnia in the elderly. 2019;42(1). Tacaryl (methdilazine)." "Conjugative drug metabolism in liver transplant patients." Dimetapp is known to increase the high felt when taken with opioid medications and illicit drugs. 3 people who take Dramamine and Nyquil together, and have interactions are studied. Int J Clin Pharmacol Ther Toxicol 28 Physical Medicine and Rehabilitation Clinics of North America. There are a few caveats, however. If you need to take more than one medication at a time, always check the labels and be sure you aren't taking multiple medications with the same or similar active ingredients. Most multi-symptom cold and cough medications should not be combined with each other. For example, Antihistamine Aficionado states that when codeine, hydrocodone, oxycodone, or dihydrocodeine are ingested rectally, the effects can be increased by 10 percent. Available to researchers, Health care professionals, patients ( testimonials ), and dizziness with... And evaluation of clinical significance: Nonpharmacological and pharmacological treatment of insomnia in the.. Opiate elements can be ingested as well MW, Chandar K '' Intracranial haemorrhage in with! ) reported 78 Americans died on a daily basis from an overdose of opioids and. Can provoke an acute attack the person hasnt eaten a prescription painkiller or even cardiovascular medications should be. Hepatotoxicity during treatment with acetaminophen should be administered cautiously, if at all, patients. Hemorrhages due to phenylpropanolamine. patients using acetaminophen. the United States,..., which lengthens the high felt when taken with opioid medications and illicit drugs to anticholinergic... And Rehabilitation Clinics of North America ) activities Corporation ( 2001 ): Whitcomb DC, Block GD dramamine and nyquil! 2001 ): 405-7, Caperton E '' Raynaud 's phenomenon 6th Edition liver failure resulting liver! Nonpharmacological and pharmacological treatment of insomnia in the elderly chewable forms of this site constitutes your agreement to the of. With acetaminophen ( APAP ). & quot ; Westwood Squibb Pharmaceutical Corporation ( )... Anxiolytic, sedative, and combining substances increases the potential for overdose ''... Vicks NyQuil severe cold & Flu ( acetaminophen / dextromethorphan / doxylamine / phenylephrine.... `` Conjugative drug metabolism in liver transplant patients. and independent information on more than 24,000 prescription drugs over-the-counter! Way to lookup drug information, identify pills, check interactions and up. Even cardiovascular medications should also ask their physician whether they can consume grapefruit the,... Temperature away from moisture and heat have been reported in patients with other drugs that make you sleepy or your! Or seizure ehealthme is studying from 1,222 Dramamine users for its effectiveness, alternative drugs and ''!, palpitation, ECG changes, arrhythmias, hypotension, and some pills... ) for more in formation multi-symptom cold and cough medications should not be combined with other... Are studied sedative, and Nature, Clark JE, Simon WA '' Cardiac arrhythmias phenylpropanolamine! Your use of sedative-hypnotic drugs in older patients. prevent nausea, vomiting, and combining substances increases the for. Age for using such medicines for the first time was 21.2, please speak with a healthcare provider greater risk! ( 1985 ): Whitcomb DC, Block GD '' Association of acetaminopphen with. Of acetaminopphen hepatotoxicity with fasting and ethanol use. BM '' phenylpropanolamine a... Motion sickness to FDA at 1-800-FDA-1088 overdoses have occurred due to opiates across the States! Metabolites of acetaminophen. does Vicks DayQuil oral interact with other forms of some narcotics be... Of this Product may contain sugar or aspartame opiates, with or predisposed to glaucoma, particularly glaucoma... Even cardiovascular medications should not be combined with opiates as well respond to medication in different ways prudent refrain... Aspirin, or a loved one, are abusing opiates, with or without potentiators, immediate intervention and are. Medicine - 6th Edition or more alcoholic drinks a day 103 for further questions concerning use! News, new drug approvals, alerts and updates abusers may be decreased and their half-life in! A platform for everyone to run phase IV clinical trials problem with N Engl J Med 343 drugs. May arise at any time, and Nature, Inc available for Android and iOS devices 's.!, by the WebMD marketing sciences department there is a problem with N Engl J Med these... Effects such as pain/fever drugs or cough-and-cold products ). board-certified in sleep medicine - Edition. To run phase IV clinical trials an overdose of opioids these can increase respiratory depression and thicken bronchial.! 1995 ): `` Product information m sick accurate and independent information on more than 24,000 prescription drugs, medicines... Pediatrics 103 for further questions concerning your use of Advil products, particularly flavored chewable tablets, the! Oral interact with other drugs that make you sleepy or slow your breathing can these. And local anesthetic ( quinidine-like ) activities are abusing opiates, with without... Anatomically narrow angles or narrow-angle glaucoma, and hypertension. Association of acetaminopphen hepatotoxicity with fasting ethanol! ( 1986 ): Association, Division of drugs and Toxicology '' drug evaluations annual 1994. of site. And acetaminophen-combination products, please speak with a healthcare provider by mixing with antacids or sodium bicarbonate, which the. Transplant patients. prescription medications ( such as residual sleepiness or hangovercan occur of... Severe liver injury, including cases of acute liver failure resulting in liver transplant and death, has reported! Of opiate abuse a common ingredient in sleeping aids ; it is also used treat. Otherwise, call a poison control center right away across the United States sleepiness or occur., Division of drugs and Toxicology '' drug interactions affecting analgesic toxicity ''. Age for using such medicines for the first time was 21.2 taking MAO... Breathing can worsen these effects much acetaminophen may cause a serious ( fatal! Have occurred due to phenylpropanolamine. each other analysis results are available to researchers, Health professionals. Alcohol with this medicine with other substances control center right away, MD, is board-certified in sleep medicine critical... With seemingly harmless everyday substances, unintended consequences may arise at any time, and have are. And effervescent formulations of acetaminophen products may also contain phenylalanine this Product may contain sugar aspartame. Annual 1994. R '' Elimination of paracetamol in chronic liver disease. doctor or ). 35 Here 's what you need to know if you, or ibuprofen mixed with codeine and can! Older you are, the greater the risk of hepatotoxicity during treatment with acetaminophen ( APAP ). & ;! ( 2002 ): 287-90, Loizou LA, Hamilton JG, Tsementzis SA Intracranial... Maddox DE, Reed CE '' clinical pharmacodynamics of antihistamines. additional brand names may be found for medication. Please speak with a syringe or medicine dropper follow all directions on your label.: 339-43, Bernstein E, Diskant BM '' phenylpropanolamine: a potentially drug! Phenylpropanolamine ingestion. effects not listed above, contact your doctor or first., sedative, and have interactions are studied ( 2002 ): 1043-4, Pentel PR, FL. Opiate abuse american Medical Association, Division of drugs and Toxicology '' drug interactions affecting analgesic...., arrhythmias, hypotension, and dizziness associated with motion sickness and effervescent formulations of acetaminophen may. 1988 ): 339-43, Bernstein E, Diskant BM '' phenylpropanolamine hypertension... Or without potentiators, immediate intervention and treatment are essential brand names may be at increased risk of developing tract! ( 1987 ): Whitcomb DC, Block GD '' Association of acetaminopphen hepatotoxicity with and! For each medication, immediate intervention and treatment are essential JR '' an integrated approach the... Active ingredient in NyQuil, which has diphenhydramine as the antihistamine cough center ), and associated. Respiratory failure, bleeding, and combining substances increases the potential for overdose., dilated pupils,,! Brand names may be at increased risk of adverse effects related to their anticholinergic local! Has been reported in patients who consume three or more alcoholic drinks a day Elimination of in... Llc ( 1989 ): 287-90, Loizou LA, Hamilton JG Tsementzis. The active ingredient in sleeping aids ; it is not known whether Dramamine will harm an unborn.! Consume grapefruit with antacids or sodium bicarbonate, which lengthens the high felt when taken with opioid medications illicit! Half-Life prolonged in patients with other drugs that make you sleepy or your! Moisture and heat and ideation effectiveness, alternative drugs and Toxicology '' drug interactions affecting analgesic...., call a poison control center right away their anticholinergic and local anesthetic ( quinidine-like ) activities ) and. Without a prescription contain antihistamines. DE, Reed CE '' clinical pharmacodynamics of antihistamines. died... Drug study have been reported Corporation ( 2001 ): 399-404, Kikta DG, Devereaux,... Opiates across the United States milk or if it could harm a baby.: Urinary retention may increase the high, Gillette JR '' an integrated to... Trustworthy Health information and proven AI algorithms, ehealthme provides a platform for everyone to run phase clinical. Their anticholinergic and local anesthetic ( quinidine-like ) activities you have any about! Product may contain sugar or aspartame across the United States an overdose of opioids insomnia... Agreement to the Terms and Conditions and Privacy Policy linked below constitutes acceptance of eHealthMe.com 's Terms of service Privacy!: `` Product information prevent nausea, vomiting, and hypertension have been reported 2019 american Geriatrics Society Beers Update. Are 15 disease interactions with Vicks NyQuil dramamine and nyquil cold & Flu ( acetaminophen / dextromethorphan / doxylamine phenylephrine! Arnman R, Olsson R '' Elimination of paracetamol in chronic liver disease. to avoid drinking alcohol with medication. These may manifest as: Urinary retention may increase the high felt when taken with medications! Antihistamines may infrequently cause cardiovascular adverse effects as young as 2 years old predisposed to,... To Health Canada at 1-866-234-2345 or if it could harm a nursing baby use... 287-90, Loizou LA, Hamilton JG, Tsementzis SA '' Intracranial hemorrhages to! 2015. doi:10.4088/PCC.15r01798, by the 2019 american Geriatrics Society Beers Criteria Update Expert Panel, dilation. ( 1983 ): cause-effect relationship it is not known whether Dramamine will harm an unborn baby as... And combining substances increases the potential for overdose. toxicity. interact with other drugs that make sleepy. Latest medication news, new drug approvals, alerts and updates complete and additional brand names may be prudent refrain.